Science Daily: When good cells go bad: Regulating the MS-causing properties of Th17 cells

| Posted in Brain Disease, Brain Education, Brain Research

Multiple sclerosis (MS) and other inflammatory autoimmune diseases are characterized by localized inflammation in various tissues, including the brain. Using a mouse model of MS, a team has identified a major regulator of Th17 cell-associated pathogenic inflammatory processes. The protein, Satb1, enhances the expression of genes promoting inflammation and suppresses genes needed to prevent autoimmunity. (February 13, 2019)

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