Brain Disease

HPC Wire: Brain Cancer, Alzheimer’s Share Cellular Process

Using the advanced computational resources at the Texas Advanced Computing Center (TACC) at The University of Texas at Austin, researchers uncovered a link between Alzheimer’s disease and cancer that may pave the way for better treatment options and new medicines. The two afflictions share a pathway in gene transcription, a process essential for cell reproduction […]

Red Orbit: Sleep Disorder Linked To Brain Disease

Researchers at the University of Toronto say a sleep disorder that causes people to act out their dreams is the best current predictor of brain diseases like Parkinson’s and Alzheimer’s. “Rapid-eye-movement sleep behavior disorder (RBD) is not just a precursor but also a critical warning sign of neurodegeneration that can lead to brain disease,” says […]

HealthDay: Certain Type of Brain Malformation May Be Best Left Alone

People with abnormal connections between arteries and veins in the brain may be less likely to suffer a stroke or die if they don’t undergo any procedures to correct the problem, new research suggests. The study included 204 patients in Scotland who had these types of abnormal connections — called “brain arteriovenous malformations” or bAVMs […]

Weill Cornell: “Chaperone” Compounds Offer New Approach to Alzheimer’s Treatment

A team of researchers from Columbia University Medical Center (CUMC), Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer’s disease involving the so-called retromer protein complex. Retromer plays a vital role in neurons, steering amyloid precursor protein (APP) away from a region of the cell where […]

Family Practice News: Asymptomatic Stenosis Could Cause Cognitive Impairment

Asymptomatic carotid stenosis may not be asymptomatic after all. Patients with a stenosis of 50% or more performed significantly worse on cognitive tests than did those without. Those cognitive issues were very likely clinically significant as well, according to a study to be presented April 30 at the annual meeting of the American Academy of […]

HealthCanal: Brain Connectivity Associated with Autism

Through this developmental lens, the San Diego State University psychology research professor hopes to understand the typical and atypical patterns of brain organization and brain connections that give rise to either normative, or abnormal behaviors, especially in the sphere of social behavior such as interacting with or understanding of others. “Social skills and the ability […]

The Score: An 18-year-old intern who kept messing up brain surgery on mice accidentally stumbled on a scientific breakthrough

The researchers found that brain damage could be significantly reduced if an antioxidant is applied immediately after the trauma. The study, which was of great interest to the NFL world, was based on the observation of mice immediately after brain trauma. In a remarkable happenstance, the study wouldn’t have been possible if Roth hadn’t been so bad […]

The Health Site: Are Brain Disorders An Evolutionary Problem?

Why is it that our Neanderthal ancestors never suffered from brain disorders like autism or schizophrenia but it’s a common malice in the modern world? The reason is that our cave-dwelling ancestors didn’t have the DNA triggers which can lead to these ailments. They were essentially turned off while the identical genes in today’s humans […]

Medical Xpress: Cancer Drugs Block Dementia-Linked Brain Inflammation, Study Finds

A class of drugs developed to treat immune-related conditions and cancer – including one currently in clinical trials for glioblastoma and other tumors – eliminates neural inflammation associated with dementia-linked diseases and brain injuries, according to UC Irvine researchers. In their study, assistant professor of neurobiology & behavior Kim Green and colleagues discovered that the drugs, […]

Red Orbit: Gene Variant Confers Higher Alzheimer’s Risk for Women

New research from scientists at Stanford University has revealed a genetic variant that raises the risk of developing Alzheimer’s disease in women, but not in men. After analyzing information on numerous older individuals who were followed over time, the scientists recognized a genetic variant called ApoE4 that conveyed the sex-specific elevated risk level, according to their report in the Annals of Neurology. […]