Brain Disease

Harvard Medical School: Brain checkpoint

Immune checkpoint therapy has transformed the way certain cancers are treated, but could a similar approach hold promise for neurodegenerative diseases such as Alzheimer’s and Parkinson’s? In a review article published in the October issue of Nature Neuroscience, Harvard Medical School investigators based at Massachusetts General Hospital have proposed that targeting immune checkpoints—molecules that regulate […]

Healthline: 4 ways depression can physically affect the brain

It’s estimated that 16.2 million adults in the United States had at least one major depressive episode in 2016. While depression can affect a person psychologically, it also has the potential to affect physical structures in the brain. These physical changes range from inflammation and oxygen restriction, to actual shrinking. (October 24, 2018) Read the […]

Spectrum: Therapy taps rhythm to boost speech in autistic children

A novel type of speech therapy may improve the verbal abilities of children with autism who speak few or no words, according to a new study1. Children with the mildest autism traits and those who speak the most consonant and vowel sounds would benefit most.The therapy, called auditory-motor mapping training (AMMT), involves the children reciting […]

Medical News Today: Does lavender really help with anxiety?

Traditional folk medicine maintains that the smell of some plants can calm the nerves. Now, new research is suggesting that one fragrant compound present in lavender can lessen anxiety by stimulating the nose to pass signals to the brain.Investigators at Kagoshima University in Japan studied the effect of linalool, a sweet-smelling alcohol that is present […]

Medical Xpress: Researchers uncover new target of alcohol in the brain

When alcohol enters the brain, it causes neurons in a specialized region called the ventral tegmental area, or VTA—also known as the “pleasure center”—to release dopamine, a neurotransmitter that produces those feel-good sensations, and tells the brain that whatever it just experienced is worth getting more of. Scientists have long sought the first step in […]

NPR: A new prescription for depression: Join a team and get sweaty

Ryan “China” McCarney has played sports his entire life, but sometimes he has to force himself to show up on the field to play pick-up soccer with his friends. “I’m dreading and I’m anticipating the worst. But I do it anyway. And then, it’s a euphoric sensation when you’re done with it because you end […]

Futurity: ‘Waste removal system’ could deliver drugs to brain

Many promising therapies for diseases of the central nervous system have failed in clinical trials because of the difficulty in getting enough of the drugs into the brain to be effective. This is because the brain maintains its own closed environment that is protected by a complex system of molecular gateways—called the blood-brain barrier—that tightly […]

News-Medical: Epigenetic modifications may contribute to Alzheimer’s disease

An international team of researchers has made an important discovery about the epigenetics involved in Alzheimer’s disease that could aid the identification of effective treatments in the future.The research, which was led by the University of Exeter and the University of Essex, investigated changes in gene activity that are not caused by DNA mutation. These […]

Medical Xpress: Study points to new method to deliver drugs to the brain

Researchers at the University of Rochester Medical Center (URMC) have discovered a potentially new approach to deliver therapeutics more effectively to the brain. The research could have implications for the treatment of a wide range of diseases, including Alzheimer’s, Parkinson’s, ALS, and brain cancer. (October 18, 2018) Read the full article here